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Publication profile

Marit Holden

Marit, Holden
Name: Marit Holden
Title: Sjefsforsker / Chief Research Scientist
Phone: (+47) 22852677, 99408505
Email: Marit [dot] Holden [at] nr [dot] no
Scientific areas: Bioinformatics, Functional genomics, Image analysis, Pattern recognition, Deep learning, Markov Chain Monte Carlo (MCMC) simulation,
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    Academic journal articles

    2018

    Aqrawi, Lara Adnan; Jensen, Janicke Liaaen; Øijordsbakken, Gunnvor; Ruus, Ann-Kristin; Nygård, Ståle; Holden, Marit; Jonsson, Roland; Galtung, Hilde; Skarstein, Kathrine. Signalling pathways identified in salivary glands from primary Sjögren's syndrome patients reveal enhanced adipose tissue development. Autoimmunity (ISSN 0891-6934). 51(3) pp 135-146. doi: 10.1080/08916934.2018.1446525. 2018.

    Skeie, Ragnhild Bieltvedt; Berntsen, Terje Koren; Aldrin, Magne Tommy; Holden, Marit; Myhre, Gunnar. Climate sensitivity estimates - Sensitivity to radiative forcing time series and observational data. Earth System Dynamics (ISSN 2190-4979). 9(2) pp 879-894. doi: 10.5194/esd-9-879-2018. 2018.

    2017

    Holden, Marit; Holden, Lars; Olsen, Karina Standahl; Lund, Eiliv. Local In Time Statistics for detecting weak gene expression signals in blood – illustrated for prediction of metastases in breast cancer in the NOWAC Post-genome Cohort. Advances in Genomics and Genetics (ISSN 1179-9870). 7 pp 11-28. doi: 10.2147/AGG.S130004. 2017. Institutional archive  Full-text 

    Simovski, Boris; Vodak, Daniel; Gundersen, Sveinung; Domanska, Diana Ewa; Azab, Abdulrahman; Holden, Lars; Holden, Marit; Grytten, Ivar; Rand, Knut Dagestad; Drabløs, Finn; Johansen, Morten; Mora Ortiz, Antonio Carlos; Lund-Andersen, Christin; Fromm, Bastian; Eskeland, Ragnhild; Gabrielsen, Odd Stokke; Ferkingstad, Egil; Nakken, Sigve; Bengtsen, Mads; Nederbragt, Alexander Johan; Thorarensen, Hildur Sif; Akse, Johannes Andreas; Glad, Ingrid Kristine; Hovig, Johannes Eivind; Sandve, Geir Kjetil. GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome. GigaScience (ISSN 2047-217X). 6(7) pp 1-12. doi: 10.1093/gigascience/gix032. 2017. Institutional archive  Full-text 

    2016

    Lund, Eiliv; Holden, Lars; Bøvelstad, Hege; Plancade, Sandra Caroline; Mode, Nicolle; Günther, Clara-Cecilie; Nuel, Gregory; Thalabard, Jean-Christophe; Holden, Marit. A new statistical method for curve group analysis of longitudinal gene expression data illustrated for breast cancer in the NOWAC postgenome cohort as a proof of principle. BMC Medical Research Methodology (ISSN 1471-2288). 16(28) doi: 10.1186/s12874-016-0129-z. 2016. Institutional archive 

    Myhrstad, Mari; Ottestad, Inger; Günther, Clara-Cecilie; Ryeng, Einar; Holden, Marit; Nilsson, Astrid; Brønner, Kirsti Wettre; Kohler, Achim; Borge, Grethe Iren Andersen; Holven, Kirsten Bjørklund; Ulven, Stine Marie. The PBMC transcriptome profile after intake of oxidized versus high-quality fish oil: an explorative study in healthy subjects. Genes & Nutrition (ISSN 1555-8932). 11:16 doi: 10.1186/s12263-016-0530-6. 2016. Institutional archive 

    2015

    Eikvil, Line; Jenssen, Tor-Kristian; Holden, Marit. Multi-focus cluster labeling. Journal of Biomedical Informatics (ISSN 1532-0464). 55 pp 116-123. doi: 10.1016/j.jbi.2015.03.012. 2015.

    Lau, Corinna; Nygård, Ståle; Fure, Hilde; Olstad, Ole Kristoffer; Holden, Marit; Lappegård, Knut Tore; Brekke, Ole Lars; Espevik, Terje; Hovig, Johannes Eivind; Mollnes, Tom Eirik. CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray. PLoS ONE (ISSN 1932-6203). 10(2) doi: 10.1371/journal.pone.0117261. 2015. Institutional archive 

    Lau, Corinna; Olstad, Ole Kristoffer; Holden, Marit; Nygård, Ståle; Fure, Hilde; Lappegård, Knut Tore; Brekke, Ole Lars; Espevik, Terje; Hovig, Johannes Eivind; Mollnes, Tom Eirik. Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response. Genomics Data (ISSN 2213-5960). 5 pp 176-183. doi: 10.1016/j.gdata.2015.05.019. 2015. Institutional archive 

    Omair, Ahmad; Mannion, Anne F.; Holden, Marit; Fairbank, Jeremy; Lie, Benedicte Alexandra; Hägg, Olle; Fritzell, Peter; Brox, Jens Ivar. Catechol-O-methyltransferase (COMT) gene polymorphisms are associated with baseline disability but not long-term treatment outcome in patients with chronic low back pain. European spine journal (ISSN 0940-6719). 24(11) pp 2425-2431. doi: 10.1007/s00586-015-3866-5. 2015.

    Omair, Ahmad; Mannion, Anne F.; Holden, Marit; Leivseth, Gunnar; Fairbank, Jeremy; Hägg, Olle; Fritzell, Peter; Brox, Jens Ivar. Age and pro-inflammatory gene polymorphisms influence adjacent segment disc degeneration more than fusion does in patients treated for chronic low back pain. European spine journal (ISSN 0940-6719). pp 2-13. doi: 10.1007/s00586-015-4181-x. 2015.

    2014

    Eikvil, Line; Holden, Marit. Evaluation of Binary Descriptors for Fast and Fully Automatic Identification. IEEE Computer Society (ISSN 1051-4651). pp 154-159. doi: 10.1109/ICPR.2014.36. 2014.

    Myhrstad, Mari; Ulven, Stine Marie; Günther, Clara-Cecilie; Ottestad, Inger; Holden, Marit; Ryeng, Einar; Borge, Grethe Iren Andersen; Kohler, Achim; Brønner, Kirsti Wettre; Thoresen, Magne; Holven, Kirsten Bjørklund. Fish oil supplementation induces Expression of genes related to cell cycle, endoplasmic reticulum stress and apoptosis in peripheral blood mononuclear cells: a transcriptomic approach. Journal of Internal Medicine (ISSN 0954-6820). 276(5) pp 498-511. doi: 10.1111/joim.12217. 2014. Institutional archive 

    Paulsen, Jonas; Rødland, Einar Andreas; Holden, Lars; Holden, Marit; Hovig, Johannes Eivind. A statistical model of ChIA-PET data for accurate detection of chromatin 3D interactions. Nucleic Acids Research (ISSN 0305-1048). 42(18) pp e143. doi: 10.1093/nar/gku738. 2014. Full-text 

    Skeie, Ragnhild Bieltvedt; Berntsen, Terje Koren; Aldrin, Magne Tommy; Holden, Marit; Myhre, Gunnar. A lower and more constrained estimate of climate sensitivity using updated observations and detailed radiative forcing time series. Earth System Dynamics (ISSN 2190-4979). 5(1) pp 139-175. doi: 10.5194/esd-5-139-2014. 2014.

    2013

    Lando, Malin; Wilting, Saskia M.; Snipstad, Kristin; Clancy, Trevor; Bierkens, Mariska; Aarnes, Eva-Katrine; Holden, Marit; Stokke, Trond; Sundfør, Kolbein; Holm, Ruth; Kristensen, Gunnar S Balle; Steenbergen, Renske D.M.; Lyng, Heidi. Identification of eight candidate target genes of the recurrent 3p12p14 loss in cervical cancer by integrative genomic profiling. Journal of Pathology (ISSN 0022-3417). 230(1) pp 59-69. doi: 10.1002/path.4168. 2013.

    Omair, Ahmad; Holden, Marit; Lie, Benedicte Alexandra; Reikerås, Olav; Brox, Jens Ivar. Treatment outcome of chronic low back pain and radiographic lumbar disc degeneration are associated with inflammatory and matrix degrading gene variants: a prospective genetic association study. BMC Musculoskeletal Disorders (ISSN 1471-2474). 14(105) doi: 10.1186/1471-2474-14-105. 2013.

    Sandve, Geir Kjetil; Gundersen, Sveinung; Johansen, Morten; Glad, Ingrid Kristine; Gunathasan, Krishanthi; Holden, Lars; Holden, Marit; Liestøl, Knut; Nygård, Ståle; Nygaard, Vegard; Paulsen, Jonas; Rydbeck, Halfdan; Trengereid, Kai; Clancy, Trevor; Drabløs, Finn; Ferkingstad, Egil; Kalaš, Matúš; Lien, Tonje Gulbrandsen; Rye, Morten Beck; Frigessi, Arnoldo; Hovig, Johannes Eivind. The Genomic HyperBrowser: an analysis web server for genome-scale data. Nucleic Acids Research (ISSN 0305-1048). 41(W1) pp W133. doi: 10.1093/nar/gkt342. 2013. Institutional archive 

    Schee, Kristina; Lorenz, Susanne; Worren, Merete Molton; Günther, Clara-Cecilie; Holden, Marit; Hovig, Johannes Eivind; Fodstad, Øystein; Meza, Leonardo Zepeda; Flatmark, Kjersti. Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer. PLoS ONE (ISSN 1932-6203). 8(6) doi: 10.1371/journal.pone.0066165. 2013.

    2012

    Aldrin, Magne; Holden, Marit; Guttorp, Peter; Skeie, Ragnhild Bieltvedt; Myhre, Gunnar; Berntsen, Terje Koren. Bayesian estimation of climate sensitivity based on a simple climate model fitted to observations of hemispheric temperatures and global ocean heat content. Environmetrics (ISSN 1180-4009). 23(3) pp 253-271. doi: 10.1002/env.2140. 2012.

    Bøhn, Siv Kjølsrud; Russnes, Kjell Magne; Sakhi, Amrit Kaur; Thoresen, Magne; Holden, Marit; Moskaug, Jan Øivind; Myhrstad, Mari Charlotte; Olstad, Ole Kristoffer; Smeland, Sigbjørn; Blomhoff, Rune. Stress associated gene expression in blood cells is related to outcome in radiotherapy treated head and neck cancer patients. BMC Cancer (ISSN 1471-2407). 12 doi: 10.1186/1471-2407-12-426. 2012.

    Halle, Cathinka Lønning; Andersen, Erlend K F; Lando, Malin; Aarnes, Eva-Katrine; Hasvold, Grete; Holden, Marit; Syljuåsen, Randi G.; Sundfør, Kolbein; Kristensen, Gunnar S Balle; Holm, Ruth; Malinen, Eirik; Lyng, Heidi. Hypoxia-induced gene expression in chemoradioresistant cervical cancer revealed by dynamic contrast enhanced MRI. Cancer Research (ISSN 0008-5472). 72(20) pp 5285-5295. doi: 10.1158/0008-5472.CAN-12-1085. 2012.

    Omair, Ahmad; Lie, Benedicte Alexandra; Reikerås, Olav; Holden, Marit; Brox, Jens Ivar. Genetic contribution of catechol-O-methyltransferase variants in treatment outcome of low back pain: a prospective genetic association study. BMC Musculoskeletal Disorders (ISSN 1471-2474). 13 doi: 10.1186/1471-2474-13-76. 2012.

    2011

    Halle, Cathinka Lønning; Lando, Malin; Svendsrud, Debbie Hege; Clancy, Trevor; Holden, Marit; Sundfør, Kolbein; Kristensen, Gunnar S Balle; Holm, Ruth; Lyng, Heidi. Membranous Expression of Ectodomain Isoforms of the Epidermal Growth Factor Receptor Predicts Outcome after Chemoradiotherapy of Lymph Node-Negative Cervical Cancer. Clinical Cancer Research (ISSN 1078-0432). 17(16) pp 5501-5512. doi: 10.1158/1078-0432.CCR-11-0297. 2011.

    Jemtland, Rune; Holden, Marit; Reppe, Sjur; Olstad, Ole Kristoffer; Reinholt, Finn P.; Gautvik, Vigdis Teig; Refvem, Hilde; Frigessi, Arnoldo; Houston, Brian; Gautvik, Kaare M. Molecular Disease Map of Bone Characterizing the Postmenopausal Osteoporosis Phenotype. Journal of Bone and Mineral Research (ISSN 0884-0431). 26(8) pp 1793-1801. doi: 10.1002/jbmr.396. 2011.

    Sandve, Geir Kjetil; Gundersen, Sveinung; Rydbeck, Halfdan; Glad, Ingrid Kristine; Holden, Lars; Holden, Marit; Liestøl, Knut; Clancy, Trevor; Drabløs, Finn; Ferkingstad, Egil; Johansen, Morten; Nygaard, Vegard; Tøstesen, Eivind; Frigessi, Arnoldo; Hovig, Eivind. The differential disease regulome. BMC Genomics (ISSN 1471-2164). 12 pp 353. doi: 10.1186/1471-2164-12-353. 2011. Full-text 

    2010

    Bøhn, Siv Kjølsrud; Myhrstad, Mari Charlotte; Thoresen, Magne; Holden, Marit; Karlsen, Anette; Tunheim, Siv Haugen; Erlund, Iris; Svendsen, Mette; Seljeflot, Ingebjørg; Moskaug, Jan Øivind; Duttaroy, Asim K.; Laake, Petter; Arnesen, Harald; Tonstad, Serena; Collins, Andrew Richard; Drevon, Christian A; Blomhoff, Rune. Blood cell gene expression associated with cellular stress defense is modulated by antioxidant-rich food in a randomised controlled clinical trial of male smokers. BMC Medicine (ISSN 1741-7015). 8 doi: 10.1186/1741-7015-8-54. 2010.

    Reppe, S; Refvem, Hilde; Gautvik, VT; Olstad, OK; Høvring, Per Ivar; Reinholt, Finn P.; Holden, Marit; Frigessi, Arnoldo; Jemtland, R; Gautvik, KM. Eight genes are highly associated with BMD variation in postmenopausal Caucasian women. Bone (ISSN 8756-3282). 46(3) pp 604-612. doi: 10.1016/j.bone.2009.11.007. 2010.

    Sandve, Geir Kjetil; Gundersen, Sveinung; Rydbeck, Halfdan; Glad, Ingrid Kristine; Holden, Lars; Holden, Marit; Liestøl, Knut; Clancy, Trevor; Ferkingstad, Egil; Johansen, Morten; Nygaard, Vegard; Tøstesen, Eivind; Frigessi, Arnoldo; Hovig, Eivind. The Genomic HyperBrowser: inferential genomics at the sequence level. Genome Biology (ISSN 1465-6906). 11(12) doi: 10.1186/gb-2010-11-12-r121. 2010. Project  Institutional archive 

    2009

    Holden, Lars; Hauge, Ragnar; Holden, Marit. ADAPTIVE INDEPENDENT METROPOLIS-HASTINGS. The Annals of Applied Probability (ISSN 1050-5164). 19(1) pp 395-413. doi: 10.1214/08-AAP545. 2009. Full-text 

    Lando, M; Holden, Marit; Bergersen, LC; Glad, Ingrid K; Kristensen, GB; Lyng, H; Svendsrud, Debbie H.; Stokke, Trond; Sundfør, Kolbein. Gene Dosage, Expression, and Ontology Analysis Identifies Driver Genes in the Carcinogenesis and Chemoradioresistance of Cervical Cancer. PLoS Genetics (ISSN 1553-7390). 5(11) doi: 10.1371/journal.pgen.1000719. 2009.

    2008

    Holden, Marit; Deng, Shiwei; Wojnowski, Leszek; Kulle, Bettina. GSEA-SNP: applying gene set enrichment analysis to SNP data from genome-wide association studies. Bioinformatics (ISSN 1367-4803). 24(23) pp 2784-2785. doi: 10.1093/bioinformatics/btn516. 2008.

    Nygaard, V; Liu, Fang; Holden, Marit; Kuo, Winston P.; Trimarchi, Jeff; Ohno-Machado, Lucila; Cepko, Connie L.; Frigessi, Arnoldo; Glad, Ingrid K.; Wiel, Mark A. van de; Hovig, Eivind; Lyng, H. Validation of oligoarrays for quantitative exploration of the transcriptome. BMC Genomics (ISSN 1471-2164). 9 doi: 10.1186/1471-2164-9-258. 2008.

    2007

    Fjærli, Hans Olav; Bukholm, G; Skjæret, Camilla; Holden, Marit; Nakstad, B. Cord blood gene expression in infants hospitalized with respiratory syncytial virus bronchiolitis. Journal of Infectious Diseases (ISSN 0022-1899). 196 doi: 10.1086/519168. 2007.

    2006

    Berner, Jeanne-Marie; Muller, Christoph Rainer; Holden, Marit; Wang, Junbai; Hovig, Eivind; Myklebost, Ola. Sampling effects on gene expression data from a human tumour xenograft. Scandinavian Journal of Laboratory Animal Science (ISSN 0901-3393). 33 pp 17-34. 2006.

    Fjærli, Hans Olav; Bukholm, Geir; Krog, Anne; Skjæret, Camilla; Holden, Marit; Nakstad, B. Whole blood gene expression in infants with respiratory syncytial virus bronchiolitis. BMC Infectious Diseases (ISSN 1471-2334). 6 doi: 10.1186/1471-2334-6-175. 2006.

    2005

    Frigessi, Arnoldo; Holden, Marit; Marshall, Clare; Viljugrein, Hildegunn; Stenseth, Nils Christian; Holden, Lars; Ageyev, V; Klassovskiy, NL; Ageyev, Vladimir; Klassovskiy, Nikolay. Bayesian population dynamics of interacting species: Great gerbils and fleas in Kazakhstan. Biometrics (ISSN 0006-341X). 61 2005.

    Frigessi, Arnoldo; van de Wiel, Mark; Holden, Marit; Svendsrud, Debbie H.; Glad, Ingrid Kristine; Lyng, Heidi. Genome-wide estimation of transcript concentrations from spotted cDNA microarray data. Nucleic Acids Research (ISSN 0305-1048). 33(17) doi: 10.1093/nar/gni141. 2005.

    Nygaard, Vigdis; Holden, Marit; Løland, Anders; Langaas, Mette; Myklebost, Ola; Hovig, Eivind. Limitations of mRNA amplification from small-size cell samples. BMC Genomics (ISSN 1471-2164). (6) pp 147. doi: 10.1186/1471-2164-6-147. 2005.

    2004

    Haug, O; Myklebost, Ola; Aldrin, M; Østenstad, Bjørn; Holden, M; Frigessi, Arnoldo; Sioud, Mouldy; Cekaite, Lina; Hovig, Eivind. Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method. Proteomics (ISSN 1615-9853). 4 pp 2572-2582. 2004.

    2003

    Aldrin, Magne; Holden, Marit; Schweder, Tore. Comment on Cowling's "Spatial Methods for Line Transect Surveys". Biometrics (ISSN 0006-341X). 59 pp 186-188. 2003.

    Nygaard, Vigdis; Løland, Anders; Holden, Marit; Langaas, Mette; Rue, Håvard; Liu, Fang; Myklebost, Ola; Fodstad, Øystein; Hovig, Eivind; Smith-Sørensen, Birgitte. Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance. BMC Genomics (ISSN 1471-2164). 4(11) doi: 10.1186/1471-2164-4-11. 2003. Abstract  Abstract 

    1998

    Holden, Marit; Solberg, Anne H. Schistad; Solberg, Rune. Wet snow-cover mapping by C- and L-band polarimtric SAR. Ukjent 1998.

    Holden, Marit; Solberg, Anne H. Schistad; Solberg, Rune. Wet snow-cover mapping by C- and L-band polarimetric SAR. Ukjent pp 1533-1537. 1998. Full-text 

    1997

    Holden, Marit. Examples of use of cut to shorten proofs. Ukjent 1997.

    1995

    Eikvil, Line; Aas, Kjersti; Holden, Marit. Automatic recognition of character strings in maps. Ukjent 1995.

    Holden, Marit; Steen, Erik; Lundervold, Arvid. Segmentation and visualization of brain lesions in multispectral magnetic resonance images. Computerized Medical Imaging and Graphics (ISSN 0895-6111). 19(2) pp 171-173. 1995.

    1993

    Holden, Marit; Eikvil, Line; Storvik, Geir. Methods for updating of model parameters applied within the area of symbol recognition. Ukjent 1993.

    1991

    Holden, Marit. Weak logic theory. Theoretical Computer Science (ISSN 0304-3975). 79 pp 295-321. 1991.

    Academic literature reviews

    2009

    Eikvil, Line; Holden, Marit; Huseby, Ragnar Bang. Adaptive registration of remote sensing images using supervised learning. Photogrammetric Engineering and Remote Sensing (ISSN 0099-1112). 75(11) pp 1297-1306. 2009. Full-text 

    Academic chapters

    2006

    van de Wiel, Mark; Holden, Marit; Glad, Ingrid Kristine; Lyng, Heidi; Frigessi, Arnoldo. Bayesian process-based modeling of two-channel microarray experiments estimating absolute mRNA concentrations. In: Bayesian Inference for Gene Expression and Proteomics. (ISBN 978-0-521-86092-5). pp 75-97. 2006.

    Academic lectures

    2014

    Eikvil, Line; Holden, Marit. Evaluation of binary descriptors for fast and fully automatic identification. Konferanse, International Conference on Pattern Recognition; Stockholm, 24.08.2014 - 28.08.2014.

    2011

    Günther, Clara-Cecilie; Tvete, Ingunn Fride; Holden, Marit. Statistics Forelesning kurs. Gjesteforelesning, Introduction to Microarray Technology; Oslo, 10.05.2011.

    2010

    Aldrin, Magne; Holden, Marit; Guttorp, Peter. Bayesian estimation of the climate sensitivity based on a simple climate model fitted to global temperature observations. Konferanse, International Workshop on Modern Statistics for Climate Research; Oslo, 01.02.2010 - 02.02.2010.

    Reppe, Sjur; Holden, Marit; Gautvik, Vigdis; Datta, Harish K; Gautvik, Kaare M. Postmenopausal BMD Variation is Strongly Associated with Subsets of MicroRNAs and Other Non-coding RNAs (ncRNAs) Expression Levels. Konferanse, The American Society for Bone and Mineral Research, Annual Meeting, 2010, Toronto, Ontario, Canada, 16.10.2010.

    2009

    Eikvil, Line; Holden, Marit; Huseby, Ragnar Bang. A system for adaptive image registration based on supervised learning. Konferanse, ESA-EUSC-JRC 2009, Sixth Conferenece on Image Information Mining, Madrid, 3-5 Nov. 2009, 04.11.2009. Full-text 

    2008

    Bøhn, Siv Kjølsrud; Myhrstad, Mari Charlotte; Thoresen, Magne; Holden, Marit; Tunheim, Siv Haugen; Karlsen, Anette; Svendsen, Mette; Seljeflot, Ingebjørg; Moskaug, Jan Øivind; Duttaroy, Asim K.; Laake, Petter; Drevon, Christian A; Arnesen, Harald; Tonstad, Serena; Collins, Andrew Richard; Blomhoff, Rune. Plant food phytochemicals modulate gene expression in human blood cells. Konferanse, 5th European nutrigenomics conference; potsdam, 02.09.2008 - 05.09.2008.

    Eikvil, Line; Koren, Hans; Holden, Marit. Vehicle Detection in High-Resolution Satellite Images. Konferanse, ESA-EUSC 2008: Image Information Mining: pursuing automation of geospatial intelligence for environm, 06.03.2008. Full-text 

    Eikvil, Line; Holden, Marit; Huseby, Ragnar Bang. Adaptive Co-Registration of Remote Sensing Images. Konferanse, ESA-EUSC 2008: Image Information Mining: pursuing automation of geospatial intelligence for environm, 06.03.2008. Full-text 

    2006

    Holden, Marit. Steps in a microarray study. Konferanse, Seminar on microarray technologies arranged by the Rikshospitalet-Radiumhospitalet Medical Center; Oslo, 24.11.2006.

    Holden, Marit. Parallelization of TransCount - making MCMC parallel for huge datasets. Konferanse, High Performance Computing for Statistical Inference, Dublin, August 23-25, 2006., 23.08.2006.

    2005

    Holden, Marit. Logic regression used for statistical analysis of SNP data obtained in genetic association studies. Konferanse, Talk at UMB, Ås, 14.06.2005.

    Holden, Marit. Model-based estimation of transcript concentrations from spotted microarray data. Konferanse, 25th European Meeting of Statisticians, July 24-28, 2005, Oslo, Norway, 24.07.2005.

    Holden, Marit. Experimental design and non-random variation. Konferanse, Lecture at the course \Micorarray data analysis\" at the Norwegian Radium Hospital, Oslo,", 31.05.2005.

    2004

    Holden, Marit. Experimental design and non-random variation. Konferanse, Introduction to Microarray Technology; The Norwegian Radium Hospital, Oslo, 29.11.2004.

    Holden, Marit. Introduction to experimental design and statistical analysis in genetic association studies. Konferanse, Reach-out day with theme: Statistical service on experimental design and analysis of SNP experiments, 01.05.2004.

    Holden, Marit. Experimental design, repeated measurements and control spots. Konferanse, Course in analysis of microarray data; Bergen, 03.02.2004.

    2003

    Holden, Marit. Forsøksdesign for cDNA mikromatriser. Foredrag. Konferanse, Ahus (Universitetssykehuset i Akershus), 01.12.2003.

    Holden, Marit. Estimation of absolute mRNA concentrations from cDNA microarrays. Konferanse, Norevent's 3rd Lysebu meeting, 01.09.2003.

    Holden, Marit. Experimental design, repeated measurements and controls. Konferanse, User course in microarray technology; The Norwegian Radium Hospital, Oslo, 14.05.2003.

    Holden, Marit. Experimental design, repeated measurements and control spots. Konferanse, User course in microarray technology; The Norwegian Radium Hospital, Oslo, 14.05.2003.

    2002

    Holden, Marit; Løland, Anders; Langaas, Mette; Rue, Håvard; Nygaard, Vigdis; Myklebost, Ola; Hovig, Eivind. Investigating the linearity of an RNA-amplification protocol using analysis of variance on data from cDNA microarray experiments. Konferanse, 19th Nordic Conference on Mathematical Statistics, 09.06.2002.

    Holden, Marit. Bildeanalyse av mikromatrisedata. Konferanse, NOBIMs industriseminar i bildeanalyse. Tønsberg, 24.10.2002.

    2000

    Solberg, Rune; Holden, Marit. A new method for sub-pixel snow-cover mapping using hyperspectral imagery. Konferanse, NOBIM-konferansen, 06.06.2000. Full-text 

    1998

    Holden, Marit. Segmentation and Visualization of Brain Lesions in Multispectral Magnetic Resonance Images. Konferanse, Workshop on Models and Methods for Spatial and Spatio-temporal Data, München,, 19.10.1998.

    1993

    Holden, Marit; Eikvil, Line; Storvik, Geir Olve. Methods for updating of model parameters applied within the area of symbol recognition. Konferanse, The 8th SCIA Conference; Tromsø, Norway, 01.01.1993.

    1992

    Holden, Marit. Oppdatering av parameterestimater. Konferanse, Bildebehandlingsseminar; Institutt for Informatikk, Universitetet i Oslo, 09.11.1992.

    Scientific lectures

    2017

    Nøst, Therese Haugdahl; Holden, Marit; Bøvelstad, Hege; Rylander, Charlotta; Lund, Eiliv; Sandanger, Torkjel M. Subtle alterations in gene expression detected in blood prior to metastatic lung cancer diagnosis – the NOWAC study. Konferanse, The 24th Norwegian Epidemiology Conference; Tromsø, 07.11.2017 - 08.11.2017.

    Posters at scientific conferences

    2016

    Olsen, Karina Standahl; Holden, Lars; Bøvelstad, Hege; Plancade, Sandra; Günther, Clara-Cecilie; Thalabard, Jean-Christophe; Holden, Marit; Lund, Eiliv. Blood gene expression profiles reflect temporality and clinical parameters up to six years before breast cancer diagnosis – The Norwegian Women and Cancer Post-genome cohort (Kvinner og Kreft-studien). 1st International NTNU Symposium on clinical biomarkers of cancer; Trondheim, 16.06.2016 - 17.06.2016.

    Olsen, Karina Standahl; Holden, Lars; Bøvelstad, Hege; Plancade, Sandra; Günther, Clara-Cecilie; Thalabard, Jean-Christophe; Holden, Marit; Lund, Eiliv. Blood gene expression profiles reflect temporality and clinical parameters up to six years before breast cancer diagnosis – The Norwegian. Norsk Forening for epidemiologi; Bergen, 26.09.2016 - 27.09.2016.

    2012

    Skeie, Ragnhild Bieltvedt; Berntsen, Terje Koren; Aldrin, Magne; Holden, Marit; Myhre, Gunnar. Constraining climate sensitivity by observations and models. European Geosciences Union General Assembly 2012; Wien, 22.04.2012 - 27.04.2012.

    2009

    Reppe, Sjur; Refvem, Hilde; Gautvik, Vigdis Teig; Olstad, Ole Kristoffer; Høvring, Per Ivar; Reinholt, Finn P.; Holden, Marit; Frigessi, Arnoldo; Jemtland, Rune; Gautvik, Kaare M. Eight Genes are Highly Associated with BMD variation in Postmenopausal Caucasian Women. 31th Annual meeting of the American Society for Bone and Mineral Research Denver Colorado 2009, 11.09.2009 - 15.09.2009.

    2005

    Frigessi, Arnoldo; Wiel, Mark A. van de; Holden, Marit; Svendsrud, Debbie H.; Glad, Ingrid K.; Lyng, Heidi. Absolute mRNA concentrations from MA-data. 8th International Meeting of the Microarray Gene Expression Data Society, 11.09.2005.

    Reports

    2018

    Holden, Marit; Holden, Lars. Parity and breast cancer - Gene expression in blood, normal and tumor tissue. Norsk Regnesentral, . NR-notat SAMBA/02/18. pp 25. 2018.

    2016

    Eikvil, Line; Holden, Marit. Fjerning av støy fra historiske dokumenter. Norsk Regnesentral, . NR-notat SAMBA/24/16. pp 38. 2016.

    Holden, Marit; Holden, Lars. Detecting weak gene expression signals in blood before diagnosis of cancer - Comparing breast, ovarian and lung cancer. Norsk Regnesentral, Oslo. NR-notat SAMBA/28/16. pp 32. 2016.

    Holden, Marit; Holden, Lars. Parity, breast cancer and gene expression. Norsk Regnesentral, Oslo. NR-notat SAMBA/19/16. pp 25. 2016.

    Holden, Marit; Holden, Lars. Analysis of gene expression in blood before diagnosis of ovarian cancer - Different statistical methods. Norsk Regnesentral, Oslo. NR-notat SAMBA/10/16. pp 36. 2016. Full-text 

    Holden, Marit; Holden, Lars. Statistical analysis of gene expression in blood before diagnosis of breast cancer. Norsk Regnesentral, Oslo. NR-notat SAMBA/07/16. pp 39. 2016. Full-text 

    Løland, Anders; Holden, Marit. Smoothing of forward curves. Norsk Regnesentral, Oslo. NR-notat SAMBA/25/16. pp 22. 2016.

    2015

    Eikvil, Line; Holden, Marit. Bruk av fargedeskriptorer for gjenkjenning av ukeblader. Norsk Regnesentral, Oslo. NR-notat SAMBA/19/15. pp 30. 2015.

    Eikvil, Line; Holden, Marit. Utvalg av deskriptorer for oppbygging av database. Norsk Regnesentral, Oslo. NR-notat SAMBA/25/15. pp 27. 2015.

    Eikvil, Line; Holden, Marit. Verifikasjon av strekkoder. Norsk Regnesentral, Oslo. NR-notat SAMBA/36/15. pp 41. 2015.

    Holden, Marit; Günther, Clara-Cecilie; Holden, Lars. Verification of a blood-based test for breast-cancer (BLOBREC) - Distinguishing breast-cancer patients from population-based controls. Norsk Regnesentral, Oslo. NR-notat SAMBA/33/15. pp 36. 2015. Full-text 

    Holden, Marit; Holden, Lars. Blood-based diagnostic tests for breast cancer:Additional subgroup analyses of the BLOBREC test. Norsk Regnesentral, Oslo. NR-notat SAMBA/44/15. pp 30. 2015.

    Lund, Eiliv; Holden, Lars; Bøvelstad, Hege; Plancade, Sandra Caroline; Mode, Nicolle; Günther, Clara-Cecilie; Nuel, Gregory; Thalabard, Jean-Christophe; Holden, Marit. Curve groups and breast cancer. Norsk Regnesentral, Oslo. NR-notat SAMBA/18/15. pp 32. 2015.

    2014

    Eikvil, Line; Holden, Marit. Robust klassifikasjon av ukeblader. Norsk Regnesentral, . NR-notat SAMBA/17/14. pp 18. 2014.

    Günther, Clara-Cecilie; Holden, Marit; Holden, Lars. Preprocessing of gene-expression data related to breast cancer diagnosis. Norsk Regnesentral, . NR-notat SAMBA/35/14. pp 41. 2014.

    Günther, Clara-Cecilie; Holden, Marit; Holden, Lars. Preprocessing of gene-expression data related to breast cancer diagnosis – extended version. Norsk Regnesentral, . NR-notat SAMBA/32/14. 2014.

    Holden, Lars; Eikvil, Line; Holden, Marit; Boudko, Svetlana. Historisk informasjon fra avisarkiv. Norsk Regnesentral, Oslo. NR-notat SAMBA 51/14. pp 41. 2014.

    Holden, Marit; Holden, Lars. Statistical analysis of gene expression data related to breast cancer diagnosis. Norsk Regnesentral, Oslo. NR-notat SAMBA/19/14. pp 74. 2014. Full-text 

    2013

    Eikvil, Line; Holden, Marit. Descriptors and matching for real-time recognition of planar and curved objects. Norsk Regnesentral, . NR-notat SAMBA/3/13. pp 39. 2013.

    Eikvil, Line; Holden, Marit. Metoder og programmer for gjenkjenning av ukeblader. Norsk Regnesentral, . NR-notat SAMBA/19/13. pp 18. 2013.

    2012

    Aas, Kjersti; Holden, Marit. Importance Sampling from DNB's Credit Risk Model. Norsk Regnesentral, Oslo. NR-notat SAMBA/31/12. pp 30. 2012.

    Eikvil, Line; Holden, Marit. Detectors and descriptors for real-time recognition of planar objects. Norsk Regnesentral, . NR-notat SAMBA/03/12. pp 23. 2012.

    Holden, Marit; Eikvil, Line. Detecting beads in time series of DNA-sequencing images. Norsk Regnesentral, . NR-notat SAMBA/57/12. pp 35. 2012.

    Holden, Marit; Glad, Ingrid Kristine; Hauge, Håvard Hildeng; Hovig, Eivind; Liestøl, Knut. Image restoration and analysis of biomolecular radioactivity images II. Norsk Regnesentral, . NR-notat SAMBA/11/12. pp 48. 2012.

    Løland, Anders; Holden, Marit. ProPrice Interface Specification. Norsk Regnesentral, . NR-notat SAMBA/29/12. pp 19. 2012.

    2011

    Eikvil, Line; Holden, Marit. Efficient search for biomedical information. Norsk Regnesentral, . NR-notat SAMBA/54/11. pp 45. 2011.

    Holden, Marit; Aas, Kjersti. Parallellisering av Totalrisiko-programmet ved hjelp av GPU. Norsk Regnesentral, . NR-notat SAMBA/13/2011. pp 14. 2011.

    Holden, Marit; Aas, Kjersti. Parallellisering av simulering fra vines. Norsk Regnesentral, . NR-notat SAMBA/18/2011. pp 13. 2011.

    Kvaal, Sigrid Ingeborg; Eikvil, Line; Holden, Marit. Bildeanalyse av røntgenbilder til hjelp for aldersvurdering. Norsk Regnesentral, . NR-notat SAMBA/43/11. pp 28. 2011. Full-text 

    2010

    Holden, Marit; Aas, Kjersti. Parallellisering av Kredittrisiko-programmet. Norsk Regnesentral, Oslo. NR-notat SAMBA/49/10. pp 16. 2010.

    Holden, Marit; Aas, Kjersti. Parallellisering av Totalrisiko-programmet. Norsk Regnesentral, Oslo. NR-notat SAMBA/43/10. pp 14. 2010.

    2009

    Eikvil, Line; Holden, Marit; Huseby, Ragnar Bang. MIR - Multiple Image Registration, Technical Documentation. Norsk Regnesentral, Oslo. NR-notat SAMBA/12/09. pp 160. 2009.

    Eikvil, Line; Holden, Marit; Huseby, Ragnar Bang. MIR - Multiple Image Registration, Software Documentation. Norsk Regnesentral, Oslo. NR-notat SAMBA/11/09. pp 138. 2009.

    2008

    Amlien, Jostein; Holden, Marit; Larsen, Siri Øyen; Trier, Øivind Thorvald Due; Solberg, Rune. CultSearcher – Software Guide, version 2. Computer-assisted detection of potential cultural heritage sites. Norsk Regnesentral, Oslo. NR-notat SAMBA/15/08. pp 42. 2008. Full-text 

    Holden, Marit; Glad, Ingrid Kristine; Hauge, Håvard Lilledalen; Liestøl, Knut. Image restoration and analysis of biomolecular radioactivity images. Norsk Regnesentral, Oslo. NR-notat SAMBA/27/08. pp 34. 2008. Full-text 

    2007

    Amlien, Jostein; Holden, Marit; Larsen, Siri Øyen; Solberg, Rune. CultSearcher - Computer-assisted detection of potential cultural heritage sites. Norsk Regnesentral, Oslo. NR-notat SAMBA/39/07. pp 39. 2007.

    Aurdal, Lars; Eikvil, Line; Koren, Hans; Hanssen, Jan Usterud; Johansen, Kjell; Holden, Marit. Road Traffic Snapshot. Norsk Regnesentral, Oslo. Report at the Norwegian Computing Center 1015. pp 71. 2007. Full-text 

    2004

    Follestad, Turid; Langaas, Mette; Rue, Håvard; Holden, Marit; Løland, Anders. glme: a C-program for parameter estimation using Gibbs-sampling in large linear mixed-effects models, with applications to DNA microarray data. Department of Mathematical Sciences, NTNU, Trondheim. Preprint Series in Statistics 2/2004. pp 20. 2004. Full-text 

    Frigessi, Arnoldo; Van der Wiel, Mark; Holden, Marit; Glad, Ingrid Kristine; Lyng, Heidi; Wiel, Mark A. van de; Glad, Ingrid K.. Model-based estimation of transcript concentrations from spotted microarray data. Norsk Regnesentral, Oslo. Report at the Norwegian Computing Center 999. pp 40. 2004. Full-text  Full-text 

    2003

    Holden, Marit; Haug, Ola. Experimental design and statistical analysis of SNP data obtained in genetic association studies. Norsk Regnesentral, Oslo. NR-notat SAMBA/28/03. pp 32. 2003. Full-text 

    Marshall, Clare; Frigessi, Arnoldo; Holden, Marit; Viljugrein, Hildegunn; Stenseth, Nils Christian; Holden, Lars; Ageyev, Vladimir; Klassovskiy, Nikolay. A Bayesian model for the population dynamics of two interacting species, with application to great gerbils and fleas in south-eastern Kazakhstan. , . 994. pp 19. 2003.

    2001

    Aldrin, Magne; Holden, Marit; Schweder, Tore. Estimation of a Neyman-Scott process from line transect data by a one-dimensional K-function. Norsk Regnesentral, Oslo. NR-notat SAMBA/18/01. pp 11. 2001. Full-text 

    2000

    Holden, Marit; Solberg, Rune. SnowStar - Teknisk dokumentasjon for SnowStar Server. Norsk Regnesentral, Oslo. NR-notat SAMBA/29/00. pp 18. 2000.

    Holden, Marit; Solberg, Rune. SnowStar - Brukerveiledning for SnowStar Server. Norsk Regnesentral, Oslo. NR-notat SAMBA/28/00. pp 18. 2000.

    Huseby, Ragnar Bang; Holden, Marit. Locating pipes in cross-profiles - documentation of C++ code. Norsk Regnesentral, Oslo. NR-notat SAMBA/22/00. pp 29. 2000.

    Huseby, Ragnar Bang; Holden, Marit. Locating pipes in cross-profiles - documentation of methods and results. Norsk Regnesentral, Oslo. NR-notat SAMBA/21/00. pp 23. 2000.

    Marshall, Clare; Frigessi, Arnoldo; Stenseth, Nils Christian; Holden, Marit; Ageyev, Vladimir; Klassovskiy, Nikolay. Plague in Kazakhstan: a bayesian model for the temporal dynamics of a vector-transmitted infectious disease. , . 959. pp 20. 2000.

    1999

    Eikvil, Line; Holden, Marit; Solberg, Anne H. Schistad. Seismic Attribute Analysis, Part IV. Norsk Regnesentral, Oslo. NR-notat SAMBA/17/99. pp 76. 1999.

    1998

    Holden, Marit; Solberg, Anne H. Schistad; Solberg, Rune. Snow mapping by multifrequency polarimetric SAR - An investigation of EMISAR data from the EMAC'95 snow campaign in Norway. , . 934. 1998.

    Solberg, Anne H. Schistad; Holden, Marit; Storvik, Geir; Teigland, André; Møller-Holst, Johan. Seismic image analysis: 3D texture attributes and classification - part III. Norsk Regnesentral, Oslo. NR-notat SAMBA/21/98. 1998.

    1997

    Holden, Marit; Solberg, Anne H. Schistad; Storvik, Geir; Teigland, André; Møller-Holst, Johan; Berge, Anker M.. Seismic image analysis: 3D texture attributes and classification - part II. Norsk Regnesentral, Oslo. NR-notat BILD/07/97. pp 60. 1997.

    1994

    Holden, Marit; Maartmann-Moe, Erling. Automatic interpretation of incoming mail in administrative environments. Norsk Regnesentral, Oslo. NR-notat BILD/04/94. pp 21. 1994.

    Holden, Marit. Segmentation of MR images of the head using a hierarchical method. , . 881. pp 25. 1994.

    1993

    Dahle, Øivind; Holden, Marit. Image acquisition and pre-processing methods for machine vision sensors. , . 864. pp 63. 1993.

    Holden, Marit; Koren, Hans. Theory and methods for automatic training and updating. Norsk Regnesentral, Oslo. NR-notat BILD/08/93. pp 26. 1993.

    Holden, Marit; Steen, Erik; Lundervold, Arvid. Segmentation and visualization of brain lesions in multispectral magnetic resonance images. Norsk Regnesentral, . pp 37. 1993.

    Holden, Marit; Aas, Kjersti; Lundervold, Arvid; Milvang, Otto; Storvik, Geir; Sebastini, Giovanni; Godtlibsen, Fred; Kristoffersen, Doris Tove. Assessment of tissue perfusion and characterization of lesions in dynamical MRI using contrast agents and statistical analysis - methodological considerations and clinical applications. Norsk Regnesentral, Oslo. NR-notat BILD/10/93. pp 70. 1993.

    Storvik, Geir; Lundervold, Arvid; Holden, Marit; Farrants, George. Diagnostic evaluation of contrast agents in medical imaging - proposals towards quantitative assessment. Norsk Regnesentral, Oslo. NR-notat BILD/03/93. pp 100. 1993.

    1992

    Bosnes, Vidar; Holden, Marit; Storvik, Geir Olve; Bosnes, Vidar. Multispectral analysis and classification system (cxxmacs): Users manual. Norsk Regnesentral, Oslo. Report at the Norwegian Computing Center 863. pp 86. 1992.

    Bosnes, Vidar; Blomlie, Viggo; Hald, John Kløve; Holden, Marit; Høgåsen, Gutorm Thomas; Lundervold, Arvid; Milvang, Otto; Storvik, Geir Olve; Øksendal, Anders; Aas, Kjersti. An evaluation of statistical modeling in magnetic resonance imaging using images fron the central nervous system aquired with and without a Gladolium-based contrast medium. Norsk Regnesentral, Oslo. Report at the Norwegian Computing Center 855. pp 47. 1992.

    Eikvil, Line; Holden, Marit; Storvik, Geir Olve. Methods for updating of model parameters applied within the area of symbol recognition. Norsk Regnesentral, Oslo. Report at the Norwegian Computing Center 859. pp 30. 1992.

    Holden, Marit; Milvang, Otto; Aas, Kjersti. Analysis of frequency information in echocardiographic radio-frequency data acquired in the presence or absance of a contrast agent (Albunex). Norsk Regnesentral, Oslo. NR-notat BILD/04/92. 1992.

    Storvik, Geir Olve; Bosnes, Vidar; Holden, Marit; Bosnes, Vidar. Improving statistical image classification by updating model parameters using unclassified pixels. Norsk Regnesentral, Oslo. Report at the Norwegian Computing Center 857. pp 26. 1992.

    Popular scientific lectures

    2009

    Tvete, Ingunn Fride; Holden, Marit. Introductory microarray course; statistics. , .

    2008

    Tvete, Ingunn Fride; Holden, Marit. Introductory microarray course; statistics. , .

    2006

    Holden, Marit; Haug, Ola; Frigessi, Arnoldo. Finding differentially expressed genes from microarray data. , .

    2005

    Holden, Marit; Løland, Anders; Neef, Linda Reiersølmoen; Haug, Ola; Frigessi, Arnoldo. Statistics and Bioinformatics. , .

    Holden, Marit. Funksjonell genomforskning, bioinformatikk og statistikk. Temakveld om bioinformatikk/medisinsk statistikk, Norsk Statistisk Forening avdeling Oslo, 30.11.2005.

    2004

    Holden, Marit. Course in statistics for molecular biologists. Bergen, 07.12.2004.

    2002

    Holden, Marit. Klustring av mikromatrisedata. Kurs for Interagon, 18.04.2002.

    Articles in business, trade and industry journals

    2003

    Holden, Marit; Løland, Anders. Introduksjon til analyse av cDNA mikromatrisedata. Norsk Epidemiologi (ISSN 0803-2491). pp 132291-296. 2003.

    2002

    Aldrin, Magne; Schweder, Tore; Holden, Marit. Spatial distribution of whales based on the Norwegian Minke Whale Survey 1996-2001. Ukjent. 2002. Full-text 

    1997

    Holden, Marit. Use of cut to obtain a characterization of the Kalmar elementary functions. Technical Report Department of Informatics. (254, ISBN 82-7368-174-2) 1997.

    1996

    Holden, Marit. A proof theoretic characterization of the Kalmar elementary functions. Technical Report Department of Informatics. (211, ISBN 82-7368-124-6) 1996.

    1988

    Holden, Marit. Weak logic theory. Doctor Scient Thesis. (111) 1988.

    1986

    Holden, Marit. Theorem proving in classical logic applied within a logic for system specification. Research Report, Department of Informatics, University of Oslo. (99) 1986.

    1985

    Holden, Marit. Bevisføring i klassisk logikk anvendt innenfor en logikk for systemspesifikasjon. Cand. Scient thesis. 1985.

    Popular scientific articles

    2012

    Skeie, Ragnhild Bieltvedt; Berntsen, Terje Koren; Aldrin, Magne; Holden, Marit. Using modelled historical concentrations of short lived climate components to constrain the climate sensitivity. META (ISSN 1890-2987). (2) pp 8-11. 2012.

    1994

    Aas, Kjersti; Holden, Marit. Characterization of lesions in dynamical MRI using contrast agent and statistical analysis. Ukjent. pp 123-127. 14.06.1994.

    Reader opinion pieces

    2006

    Holden, Marit. Bioinformatikk-et tverrfaglig forskningsfelt. Tilfeldig gang, 2006-12-05

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